Protein Tags for Expression and Purification – What to use and pitfalls to avoid
In the quest to deliver pure recombinant protein for assay, biophysics or crystallisation, the addition of an affinity tag, to fish out the target protein […]
Alderley Park Science Poster Showcase Event 7th Nov
A great opportunity this morning for Juli and Rachel to showcase how a combination of protein […]
Peak Proteins at Bio Europe 2018
Kicking off November with a couple of European meetings, starting with Mark attending Europe’s biggest life […]
ELRIG 2018
Peak Proteins will be exhibiting at this year’s ELRIG 2018 Drug Discovery conference and running a “Problems with Proteins” drop-in clinic at their booth D5 on […]
Cell culture considerations for protein expression
Want to know more about factors to consider when expressing proteins in eukaryotic cells? Have a […]
The trials, tribulations and joy of protein crystallisation
Despite the recent success of cryoEM in solving more protein structures, X-ray crystallography remains the best method to obtain high resolution (≤3 […]
Protein refolding – easy or excruciating?
In a previous blog, we mentioned the theory of Anfinsen that the structure of a protein is determined solely by the amino acid sequence and […]
Rachel takes the guesswork out of Mass Spec-ulation
A warm welcome to Rachel Rowlinson; the latest addition to our expanding team here at Peak […]
What is Fragment-Based Lead Generation (FBLG)?
Fragment-based lead generation (FBLG) is a very popular paradigm for early hit identification and lead generation and can be an attractive alternative to the more […]