News2018-11-14T14:53:52+00:00

Latest News & Insights from Peak Proteins

Protein Tags for Expression and Purification – What to use and pitfalls to avoid

Protein Tags for Expression and Purification – What to use and pitfalls to avoid

In the quest to deliver pure recombinant protein for assay, biophysics or crystallisation, the addition of an affinity tag, to fish out the target protein [...]

Alderley Park Science Poster Showcase Event 7th Nov

A great opportunity this morning for Juli and Rachel to show case how a combination of protein engineering and detailed mass spectrometry analysis of the [...]

Peak Proteins at Bio Europe 2018

Kicking of November with a couple of European meetings, starting with Mark attending Europe’s biggest life science and pharma partnering meeting, Bio Europe 2018 in [...]

ELRIG 2018

ELRIG 2018

Peak Proteins will be exhibiting at this year’s ELRIG 2018 Drug Discovery conference and running a “Problems with Proteins” drop-in clinic at their booth D5 on [...]

Cell culture considerations for protein expression

Want to know more about factors to consider when expressing proteins in eukaryotic cells? Have a read of Mark Abbott’s article in the October issue [...]

The trials, tribulations and joy of protein crystallisation

The trials, tribulations and joy of protein crystallisation

Despite the recent success of cryoEM in solving more protein structures, X-ray crystallography remains the best method to obtain high resolution (≤3 Angstroms) structures that [...]

Protein refolding – easy or excruciating?

Protein refolding – easy or excruciating?

In a previous blog we mentioned the theory of Anfinsen that the structure of a protein is determined solely by the amino acid sequence and [...]

Launching the Peak Proteins Blog page

Have a look at our new Blog Page where we aim to provide helpful thoughts and insights into all aspects of protein expression, purification, crystallography and [...]

Rachel takes the guesswork out of Mass Spec-ulation

A warm welcome to Rachel Rowlinson; the latest addition to our expanding team here at Peak Proteins. Rachel has over 20 years experience in the pharmaceutical [...]

What is Fragment-Based Lead Generation (FBLG)?

What is Fragment-Based Lead Generation (FBLG)?

  Fragment-based lead generation (FBLG) is a very popular paradigm for early hit identification and lead generation, and can be an attractive alternative to the [...]

Job vacancy for Senior or Principal Protein Scientist

Senior Scientist or Principal Scientist in protein engineering, expression and purification   We are looking for a senior or principal scientist in protein engineering, expression [...]

ELRIG 2018 Research and Innovation conference

Come and meet Mark in the Innovation Zone at ELRIG’s Research and Innovation conference in Homerton College, Cambridge and find out more about our protein [...]

A new month…..and a new addition to the team

A warm welcome to Jon Renshaw, who recently joined the team from AstraZeneca, bringing with him many years of experience in protein production, characterisation and latterly [...]

Bionow Cancer Conference 27th Feb

Looking forward to exhibiting at Bionow’s Accelerating Cancer Drug Development conference on Tues 27th Feb at Alderley Park, Cheshire. Hope to see some of you [...]

And then there were 10!

And then there were 10!

It’s certainly been a busy time over the last few months at Peak Proteins which has seen our staff numbers grow to 10. We have [...]

Peak Proteins jobs

Peak Proteins jobs

Peak Proteins is currently looking for talented and enthusiastic protein scientists to join our rapidly expanding team. In particular if you have exceptional and proven [...]

Peak Proteins’ ISO 9001 accreditation

Peak Proteins’ ISO 9001 accreditation

Peak Proteins is now registered as operating under ISO 9001 : 2015. We have received our certification in February 2017. Now all our customers have the [...]

Fragment-based hit discovery for the epigenetic target, BRD3

Fragment-based hit discovery for the epigenetic target, BRD3

Earlier this year Peak Protein’s first synchrotron trip took place to collect X-ray data on the target bromodomain 3 (BRD3) in a joint project run [...]

X-ray crystal structures of BRD3-fragment complexes presented at EFMC-ISMC 2016

X-ray crystal structures of BRD3-fragment complexes presented at EFMC-ISMC 2016

Peak Proteins presented details of a successful collaboration with Sygnature Discovery at the International Medicinal Chemistry Symposium in Manchester last week.  The project involved looking at the interactions of small [...]

FEN1-inhibitor co-crystal structure published

FEN1-inhibitor co-crystal structure published

Mark Abbott has recently co-authored a paper in Nature Chemical Biology  as part of a collaboration between AstraZeneca, University of Sheffield and Pelago BioSciences. The publication [...]