Structural Determination2018-11-14T11:57:18+00:00

Protein crystals are then frozen in preparation for X-ray data collection at the synchrotron. The output from this collection is progressed to structure solution, several rounds of refinement and then on to produce a 3D structure representation.

If there is no related structure available to permit the use of a molecular replacement option to solve the structure, we have experience of various methods of de novo phasing for new structures. Several novel proteins structures feature amongst our publications.

Our final delivery package is not just a set of co-ordinates. We supply a detailed analysis of the overall 3D structure, along with our learning and conclusions, with ideas for project progression and drug design. Ideally, this would be part of a face-to-face discussion with our clients.

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For further information or simply to say hello please contact us on 01625 238892 or email us