A CRO WITH EXPERTISE IN PROTEIN PRODUCTION, CHARACTERISATION AND STRUCTURE

Peak Proteins and IniXium are now both part of the Sygnature Discovery Group. This signifies our continued growth and global integration but won’t affect our collaboration or the services you trust. Expect the same dedication and innovative solutions.

Our services

Sygnature Protein & Structure Services

We are a contract research organisation, part of Sygnature Discovery; who provide custom-made, soluble and membrane proteins for use in drug discovery and research applications. We are one of the few CROs that provide all of the 3 main structural biology techniques in house to produce X-ray, NMR and Cryo-EM structures of both novel and precedented proteins.

We take a holistic approach, taking into account the nature of the protein target, the ultimate end use, along with your project objectives to guide construct design and then define a strategy aimed to give the highest chance of success.

Protein Expression and Protein Purification

We design, express, and purify customised soluble and membrane proteins reagents to support your research needs. We apply our expertise and knowledge to your protein of interest to provide an innovative, interactive, and flexible approach to every project.

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Protein Characterisation

We use various methods to characterise and quality control the proteins we make. We also offer some of these as standalone services to our clients, including intact protein mass spectrometry and peptide mapping, Flow induced dispersion analysis (Fida) and NMR.

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Protein Crystallography and Structure Determination

Structural Biology

Providing crystallography, Cryo-EM and NMR, our service isn’t just a final set of co-ordinates, but a detailed analysis of the 3D structure along with our learning and conclusions, driving ideas for project progression and drug design.

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