With a wealth of experience in the Drug Discovery environment, we are confident our team can fulfil your needs for any part of the Gene to Structure process.
We tailor our professional services to fit your requirements, whatever stage of the process you are at. From construct design, through to expression and purification of your desired protein. Whatever your end use, assay, high throughput screening, biophysics or crystallisation and X-ray structure determination, we can supply your protein in a suitable format.
Peak Proteins’ Services
Protein Expression and Purification
Experts in protein expression and purification of customised soluble and membrane proteins reagents, using E.coli, insect and mammalian expression systems.
Protein Crystallography and Structure Determination
Our protein crystallography and structure determination service is driven by an outstanding team of experienced crystallographers with a strong track record in solving novel and liganded protein structures to help you fully exploit structural data.
Protein Mass spectrometry
Our protein mass spectrometry service provides reliable, timely and cost-effective intact protein and peptide mapping analysis to suit your needs.
Latest News from Peak Proteins
A creative move for Margaret to the Peak Proteins team
We're delighted to have Margaret Veldman-Jones join the team to enhance our cell culture and protein expression capabilities. Find out more about Margaret's love of science, art and sport on [...]
Presentation at Biopharma Seminars Held in Hyderabad and Bangalore on 25th and 26th June.
Dr Mark Abbott, CEO of Peak Proteins, is travelling to India between the 24th and 25th of June to present a talk on “Mass Spectrometry is an Essential Tool to Understand [...]
Thermofluor Stability Assays: More Than Just Thermal Melting
At Peak Proteins, we determine the thermal melting temperature of our proteins as a routine quality control check. Thermal melting can confirm the protein is correctly folded and provide a [...]
Peak Protein Case Studies
Removing N-linked oligosaccharides to aid protein crystallisation
Removing N-linked oligosaccharides to aid protein crystallisation A client was looking to solve the crystal structure of a secreted protein which contained a number of disulphide bonds and potential N-linked glycosylation sites, which leads to the attachment of complex sugar molecules. There was already literature available describing the [...]
Time critical purification of multiple Fab constructs for assay
Time critical purification of multiple Fab constructs for assay As a leading protein purification company, BiVictriX required us to develop a method to purify 10mg each of 24 different antibody-binding fragments (Fabs) to be tested in assays. Once analysed by BiVictriX, a smaller number of chosen constructs were to [...]
Adapting use of size exclusion chromatography to improve yields of an unstable, purified protein
Adapting use of size exclusion chromatography to improve yields of an unstable, purified protein A client asked us to express and purify at least 2 mg each of two similar enzymes for selectivity assays. There was literature precedent for both proteins, and a similar approach would be taken with [...]