With a wealth of experience in the Drug Discovery environment, we are confident our team can fulfil your needs for any part of the Gene to Structure process.
We tailor our professional services to fit your requirements, whatever stage of the process you are at. From construct design, through to expression and purification of your desired protein. Whatever your end use, assay, high throughput screening, biophysics or crystallisation and X-ray structure determination, we can supply your protein in a suitable format.
Peak Proteins’ Services
We use a wide range of affinity and standard chromatography procedures to allow rapid purification of proteins according to their varied and individual characteristics such as size, charge, hydrophobicity.
Robust QC of all reagents supplied is a key part of the service we offer. Size exclusion chromatography, thermal shift and LC-MS are routinely used to characterise and verify the quality of the purified proteins we produce.
Crystallisation is far from predictable, and going from purified protein to crystals suitable for x-ray analysis can often be an arduous journey. With our extensive experience and knowledge of protein reagents, precipitant factors to vary, and the right experimental set-up to use, we aim to generate diffraction quality crystals as efficiently as possible .
Peak Protein in Numbers
Latest News from Peak Proteins
Cell culture considerations for protein expression
Want to know more about factors to consider when expressing proteins in eukaryotic cells? Have a read of Mark Abbott's article in the October issue of European Biopharmaceutical review to learn [...]
The trials, tribulations and joy of protein crystallisation
Despite the recent success of cryoEM in solving more protein structures, X-ray crystallography remains the best method to obtain high resolution (≤3 Angstroms) structures that can facilitate structure based drug [...]
