Green Team Blog 3A new way to side-step the use of crabs in endotoxin detection.In a previous blog, we discussed the amazing horseshoe crab and why its blue blood is so special. Specifically, how horseshoe crab blood is used as [...]
Rick Davies joined Sygnature Protein Science and Structural Biology (formerly Peak Proteins) as the new Director in January this year. He joins the company as a Protein Biochemist with 35 years previous experience with AstraZeneca, based in Cambridge UK. [...]
We recently hosted our colleague Hannah Rowlands for a short secondment within our Protein Science labs at Birchwood House. She reflects below on her time spent within the team. "I have been a member of the Sygnature Bioscience department at [...]
Did you know freezers are some of the most energy intensive pieces of equipment found in the lab? An ultralow temperature (ULT) freezer can consume nearly double the amount of electricity as the average 4-bedroom household per day!* Correctly [...]
Our founder Mark Abbott takes us through the story of Peak Proteins. From the initial conception to the current status as part of Sygnature Discovery. We have grown steadily over the last 10 years and have assembled a large [...]
Scott Allen talks us through his recent Professional Internship for PhD Students (PIPS) placement Over the past three months, I’ve been based at Peak Proteins (part of Sygnature Discovery), completing my PIPS placement. The PIPS scheme is an essential [...]
In this article we discuss the three techniques used for determining protein and nucleic acid structures, their individual merits, what each workflows looks like, and how they fit into drug discovery. Introduction Understanding protein structures is fundamental for unravelling [...]
In this article we discuss O-linked glycosylation of proteins and show some data from a study with the platelet receptor G6b-B to exemplify how we approach identifying the sites of sugar attachment. Glycosylation is a common post-translational modification of [...]
In recent years, structural biology has become more prevalent in biotherapeutic development playing a pivotal role in elucidating the antibody-antigen complex formation and understanding the effect on structure of introducing amino acid substitutions. By employing techniques such as X-ray [...]
Two Peak/Sygnature scientists, Juli Warwicker and Mark Abbott, have recently co-authored a paper on a new family of anti-thrombotic biotherapeutics. The paper is from the lab of Dr. Yotis Senis, Research Director, INSERM, Strasbourg, France. The Senis lab have [...]
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Email us: info@peakproteins.com
Peak Proteins is a trading name of Sygnature Discovery Limited
