Peak Proteins Membrane Proteins Archives
At Sygnature Discovery, our Protein Science department stands out for its expertise in expressing, purifying and characterising a wide range of proteins to aid assay development, mechanistic studies, and structure-based drug design. Among the most complex and valuable targets [...]
Importance of metabolic GPCRs Metabolic GPCRs play a vital role in how our bodies manage energy. These G protein-coupled receptors act like molecular switches, translating signals from hormones and nutrients into cellular actions that regulate everything from blood sugar [...]
By Steven Harborne, Senior Principal Scientist Over the coming months, we’ll be sharing a series of blog posts and case studies that aim to spotlight our work on membrane proteins: from protein production and structural biology to biophysical characterisation [...]
Here we introduce, Margeoux Dela Rosa the latest member of our membrane protein team and we start with Margeoux giving us a brief overview of her scientific journey. "It was the final year of my integrated Masters at the [...]
Ben’s PIPs Placement Journey with Peak Proteins In this article PhD Student Ben Nash discusses his 3-month PIPs placement work at Peak Proteins, which involved the expression and purification optimisation of the G-protein coupled receptor (GPCR) 5-HT2AR. Ultimately, Ben’s [...]
By Jade Bowen At Peak Proteins, we are often asked to purify a variety of complex and challenging proteins. One of the most difficult targets that we work with are membrane proteins, requiring additional steps and the use of [...]
Written by Dr. Jack Wright and Dr. Steven Harborne Over the past 5-10 years, there has been an explosion in the field of cryo-electron microscopy (cryo-EM). The resolutions that can be achieved with the latest state-of-the art equipment and [...]
Researchers from Peak Proteins (part of Sygnature Discovery Ltd.) have recently published a research paper in the Journal of Visualized Experiments. The paper entitled “Rapid Assessment of Membrane Protein Quality by Fluorescent Size Exclusion Chromatography” was authored by Dr [...]
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Peak Proteins is a trading name of Sygnature Discovery Limited
