Peak Proteins Protein Science Archives
In this mini review we discuss Alpha Synuclein (αSyn), a small, yet curious 140 amino acid long protein that was originally named because of its localisation on synaptic vesicles from the electric lobe of the Pacific Electric Ray, Torpedo [...]
Cryo-EM offers unprecedented insights into complex macromolecules, but success is dependent on the quality of your sample. At Sygnature Discovery, we’ve built a precision-focused cryo-EM lab to ensure your structural biology project starts with the best possible sample. Expertise [...]
Scott Allen talks us through his recent Professional Internship for PhD Students (PIPS) placement Over the past three months, I’ve been based at Peak Proteins (part of Sygnature Discovery), completing my PIPS placement. The PIPS scheme is an essential [...]
The intriguing world of the Intrinsically disordered proteins and why they are important as targets for drug discovery By Ariadna Juarez-Martinez PhD When we think about proteins, we usually picture them as having a well-defined, three-dimensional, globular shape; however, [...]
By Anna Bennett The beginning of your career after university can be daunting, finding yourself in a new environment where everyone around you has lot more experience than you can certainly feel like a lot of pressure. When I [...]
Written by Dr Duncan Smith and Dr Martin Jennings At Peak Proteins, we have been utilising the Fida platform (Flow Induced Dispersion Analysis) for the past six months, and it has quickly become an essential tool for our team. [...]
Written by Dr. Jack Wright and Dr. Steven Harborne Over the past 5-10 years, there has been an explosion in the field of cryo-electron microscopy (cryo-EM). The resolutions that can be achieved with the latest state-of-the art equipment and [...]
Researchers from Peak Proteins (part of Sygnature Discovery Ltd.) have recently published a research paper in the Journal of Visualized Experiments. The paper entitled “Rapid Assessment of Membrane Protein Quality by Fluorescent Size Exclusion Chromatography” was authored by Dr [...]
Recently we discovered that one of the biggest hits on our website was for our protocol on “Determining Protein Concentration by UV” which is obviously satisfying and we are glad that they are proving to be useful. We are [...]
What is Biotin? Biotin (or vitamin B7) is an essential coenzyme that is required by all organisms for life. Indeed, biotin’s name literally means ‘life giving’. Biotin is covalently linked near the active sites of four major classes of [...]
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