Interaction of the La-related protein Slf1 with colliding ribosomes maintains translation of oxidative-stress responsive mRNAs
Nucleic Acids Research, 2023
Martin D. Jennings, Priya Srivastava, Christopher J Kershaw, David Talavera, Christopher M. Grant, Graham D. Pavitt
Quantifying the Binding of Fluorescently Labeled Guanine Nucleotides and Initiator tRNA to Eukaryotic Translation Initiation Factor 2
The Integrated Stress Response pp 89–99, 2022
Martin D. Jennings and Graham D. Pavitt
GTP binding to translation factor eIF2B stimulates its guanine nucleotide exchange activity
iScience, Volume 24, Issue 12, 2021
Christopher J. Kershaw, Martin D. Jennings, Francesco Cortopassi, Margherita Guaita, Hawra Al-Ghafli and Graham D. Pavitt
Integrated multi-omics reveals common properties underlying stress granule and P-body formation
RNA Biology, 18:sup2, 655-673, 2021
Christopher J. Kershaw, Michael G. Nelson, Jennifer Lui, Christian P. Bates, Martin D. Jennings, Simon J. Hubbard, Mark P. Ashe & Chris M. Grant
Overlapping regions of Caf20 mediate its interactions with the mRNA-5′cap-binding protein eIF4E and with ribosomes
Scientific Reports volume 11, Article number: 13467 (2021)
Ebelechukwu C. Nwokoye, Eiman AlNaseem, Robert A. Crawford, Lydia M. Castelli, Martin D. Jennings, Christopher J. Kershaw & Graham D. Pavitt
Impaired eIF5A function causes a Mendelian disorder that is partially rescued in model systems by spermidine
Nature communications 2021 12 (1), 1-13
Víctor Faundes, Martin D. Jennings, Siobhan Crilly, Sarah Legraie, Sarah E Withers, Sara Cuvertino, Sally J Davies, Andrew GL Douglas, Andrew E Fry, Victoria Harrison, Jeanne Amiel, Daphné Lehalle, William G Newman, Patricia Newkirk, Judith Ranells, Miranda Splitt, Laura A Cross, Carol J Saunders, Bonnie R Sullivan, Jorge L Granadillo, Christopher T Gordon, Paul R Kasher, Graham D Pavitt, Siddharth Banka
The structural basis of translational control by eIF2 phosphorylation
Nature communications 2019 10 (1), 1-10
Tomas Adomavicius, Margherita Guaita, Yu Zhou, Martin D. Jennings, Zakia Latif, Alan M Roseman, Graham D Pavitt.
Fail-safe control of translation initiation by dissociation of eIF2α phosphorylated ternary complexes
Elife 6 2017, e24542
Martin D. Jennings, Christopher J Kershaw, Tomas Adomavicius, Graham D Pavitt
eIF2β is critical for eIF5-mediated GDP-dissociation inhibitor activity and translational control
Nucleic acids research 2016 44 (20), 9698-9709
Martin D. Jennings, Christopher J Kershaw, Christopher White, Danielle Hoyle, Jonathan P Richardson, Joseph L Costello, Ian J Donaldson, Yu Zhou, Graham D Pavitt
eIF2B promotes eIF5 dissociation from eIF2• GDP to facilitate guanine nucleotide exchange for translation initiation
Genes & development 2013 27 (24), 2696-2707
Martin D. Jennings, Yu Zhou, Sarah S Mohammad-Qureshi, David Bennett, Graham D Pavitt
eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation
Nature 465 2010 (7296), 378-381
Martin D. Jennings, Graham D Pavitt
