Peak Proteins Blog Archives
With apologies to T. S. Eliot The Naming of Proteins is a difficult matter, It isn't just one of your holiday games; You may think at first I'm as mad as a hatter When I tell you, a protein [...]
At Peak Proteins, we use mammalian, insect and bacterial cells grown in specialised culture media for the expression of recombinant proteins. A key focus for us is to ensure the expression systems we use are running optimally, in order [...]
We’re happy to share this recent open access publication out in Nature Scientific Reports: "IMPROvER the Integral Membrane Protein Stability Selector", which was authored by one of our scientists, Dr Steve Harborne. Membrane proteins are often intrinsically flexible, unstable [...]
Mass spectrometry is one of Peak Proteins’ core services. Using the Sciex ExionLC coupled to a Sciex X500B QTOF mass spectrometer with Sciex OS and BioPharmaView Software, we have the ability to perform both LC-MS intact protein analysis along [...]
by Dr. Steven Harborne and Dr. Raquel Faba Rodríguez Peak Proteins is assisting in the fight against COVID-19 by supplying protein reagents for coronavirus research. For example, we are supplying a research team from Trinity College Dublin to help [...]
In a previous blog post, we highlighted some excellent recent work that has elucidated the molecular mechanism of host-cell invasion by the novel 2019 coronavirus (2019-nCoV). Researchers provided us with three-dimensional structures of the viral spike protein using cryoEM. In [...]
In our previous blog post, we explored the solubilisation of membrane proteins in detergent, and explained why this is an important step in the production of pure, stable and active membrane protein product. In short, solubilisation is a process [...]
Walk the line In one of our previous blog posts we discussed the challenges of working with a specific sub-type of membrane proteins called G-protein coupled receptors (GPCRs). All GPCRs have seven transmembrane alpha-helices that span the plasma membrane, [...]
At Peak Proteins we routinely use protein mass spectrometry methods to fully characterise and understand the proteins we have produced in our protein expression systems. So why do we do this and what additional information do we gain, in [...]
In this article our Cells Team share some tips and tricks for improving the yields of recombinant proteins expression in mammalian cells An earlier blog outlined the benefits of using mammalian cells as an expression host. At Sygnature Discovery [...]
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Email us: info@peakproteins.com
Peak Proteins is a trading name of Sygnature Discovery Limited
