Ariadna Juarez-Martinez PhD

Senior Protein Scientist

Ariadna Juarez-Martinez has significant experience from academia in protein science and structural biology, including Cryo-EM.

Ariadna Juarez-Martinez | Senior Protein Scientist | Peak Proteins

More about Ariadna

Ariadna began her scientific career at Instituto Politécnico Nacional (IPN) in Mexico City, where she was following her passion for genetics and biochemistry by obtaining a degree in Engineering in Biotechnology. This initial step in her academic career ignited an interest in the field and motivated her to further explore the complexities of biomolecular and biomedical science. Consequently, she started a Masters degree in this area.
Driven by an insatiable curiosity to understand the mysteries of macromolecules, she further pursued her academic aspirations by earning a Ph.D. in Molecular and Cellular Science at Universidad Autónoma del Estado de Morelos and Instituto de Biotecnología-UNAM. During this transformative period, she had her first exposure to studying proteins using X-ray crystallography, which sparked a profound fascination for biophysical and structural approaches in protein research.

Motivated to expand her knowledge and expertise in this domain, Ariadna sought out opportunities at one of the most prestigious institutes for studying macromolecules, the Institute de Biologie Structurale (IBS) in Grenoble, France where she undertook a postdoctoral research position. The focus of her work was using a crystallography approach to understand the roll of meiotic DNA double-strand break formation complexes.

Continuing her scientific journey, she continued her postdoctoral research at the University of Sussex, focusing on state-of-the-art Cryo Electron Microscopy (Cryo EM) techniques. During this phase, she delved into the study of proteins involved in DNA repair processes, gaining invaluable insights into their mechanisms and functions.

Throughout her educational journey, Ariadna has acquired knowledge to understand the mysteries of life through the study of proteins with a desire to explore new avenues and apply her expertise to practical applications. With this in mind she decided to transition from academia into industry. Joining Peak Proteins will hopefully provide her with the perfect platform to develop and apply her skills.

Beyond the lab, Ariadna’s passions lie in cooking and baking. She thoroughly enjoys exploring new recipes and finding ways to enhance them. Besides that, she also finds great pleasure in going for runs to keep active and healthy. She also loves spending quality time with her family, whenever she gets the chance.

Structural analysis of Red1 as a conserved scaffold of the RNA-targeting MTREC/PAXT complex.
Foucher, A.-E., Touat-Todeschini, L., Juarez-Martinez, A. B., Rakitch, A., Laroussi, H., Karczewski, C., Acajjaoui, S., Soler-López, M., Cusack, S., Mackereth, C. D., Verdel, A., & Kadlec, J.
Nature Communications (2022). 13(1), 4969.

Crystal structure of a class-mu glutathione S-transferase from whiteleg shrimp Litopenaeus vannamei : structural changes in the xenobiotic binding H-site may alter the spectra of molecules bound.
Juárez-Martínez, A. B., Sotelo-Mundo, R. R., & Rudiño-Piñera, E.
Journal of Biochemical and Molecular Toxicology (2017). 31(2), e21838.

Detection and sequencing of defective viral genomes in C6/36 cells persistently infected with dengue virus 2.
Juárez-Martínez, A. B., Vega-Almeida, T. O., Salas-Benito, M., García-Espitia, M., De Nova-Ocampo, M., del Ángel, R. M., & Salas-Benito, J. S. Archives of Virology (2013). 158(3), 583–599.

Mouse REC114 is essential for meiotic DNA double-strand break formation and forms a complex with MEI4.
Kumar, R., Oliver, C., Brun, C., Juarez-Martinez, A. B., Tarabay, Y., Kadlec, J., & de Massy, B.
Life Science Alliance (2018). 1(6), e201800259.

Characterization of the REC114‐MEI4‐IHO1 complex regulating meiotic DNA double‐strand break formation.
Laroussi, H., Juarez‐Martinez, A. B., Le Roy, A., Boeri Erba, E., Gabel, F., de Massy, B., & Kadlec, J.
The EMBO Journal (2023). 42(16).

TOPOVIBL-REC114 interaction regulates meiotic DNA double-strand breaks.
Nore, A., Juarez-Martinez, A. B., Clément, J., Brun, C., Diagouraga, B., Laroussi, H., Grey, C., Bourbon, H. M., Kadlec, J., Robert, T., & de Massy, B.
Nature Communications (2022) 13(1), 7048.