Josh Shaw

Senior Protein Scientist

Josh has significant experience from academia and industry in both recombinant protein expression and purification

Dr Joshua Shaw | Peak Proteins

More about Josh

After graduating from the University of Sheffield with a BSc in Biomedical Science, Josh joined Gillespie Manners, as a head-hunter for the management consulting market. Working with pharmaceutical companies, Josh’s interest in drug discovery was ignited.

Josh went on to gain an MRes in tissue engineering at the University of Manchester, adapting cell culture medium components and conditions for the directed differentiation of stem cells (adult and embryonic). Building on this experience, Josh continued with a PhD where his work involved expressing recombinant vertebrate-like collagen fragments from E.coli for use as a tissue culture plastic coating, experience with mammalian expression systems and lentiviral transfection, and developing an in-depth knowledge of complex 3D cell culture systems. With his experience of 3D hydrogel culture, creating a tissue-like environment, Josh joined Manchester Biogel based at Alderley Park.

Following that Josh was interested in joining a larger company and pursuing a career in the CRO industry. The opportunity to work at Peak Proteins fit the bill perfectly and he joined the team in April 2022.

Outside of work, Josh is a keen rock climber and over the past 15 years has practiced all styles from bouldering to traditional and sport climbing. On his climbing adventures, Josh is often accompanied by his Shetland Sheepdog, Fennec. Depending on the weather, Josh can also be found tending his Bonsai in the garden or listening to audiobooks, having acquired a library of over 70 books during lockdown.

Using Stereochemistry to Control Mechanical Properties in Thiol–Yne Click‐Hydrogels
Angew. Chemie, vol. 133, no. 49, pp. 26060–26068, Dec. 2021, doi: 10.1002/ange.202107161.
L. J. Macdougall et al.

Robust alginate/hyaluronic acid thiol–yne click-hydrogel scaffolds with superior mechanical performance and stability for load-bearing soft tissue engineering
Biomater. Sci., vol. 8, no. 1, pp. 405–412, 2020, doi: 10.1039/C9BM01494B.
M. M. Pérez-Madrigal, J. E. Shaw, M. C. Arno, J. A. Hoyland, S. M. Richardson, and A. P. Dove

Self-healing, stretchable and robust interpenetrating network hydrogels
Biomater. Sci., vol. 6, no. 11, pp. 2932–2937, 2018, doi: 10.1039/C8BM00872H.
L. J. Macdougall et al.

An immortalised mesenchymal stem cell line maintains mechano-responsive behaviour and can be used as a reporter of substrate stiffness
Sci. Rep., vol. 8, no. 1, p. 8981, Dec. 2018, doi: 10.1038/s41598-018-27346-9.
A. Galarza Torre et al.

Biogelx: Cell Culture on Self-Assembling Peptide Gels
2018, pp. 283–303.
M. M. Harper et al.