We welcome Rachel Johnson, another addition to our experienced Cryo-EM team
Sygnature Discovery is delighted to welcome Rachel Johnson to the Peak Proteins team. Rachel’s arrival highlights our commitment to offering our clients an exceptional Cryo-EM and structural biology service.
Rachel has determined >20 cryo-EM structures of GPCRs allowing her to bring her expertise in sample preparation and data processing to the team. Some of her work is shown in the following papers:
We are able to support every aspect of a project from gene, through protein production to final Cryo-EM structure determination. Where we excel is being able to tackle challenging protein targets. Often the key to success for any protein structure project is being able to produce high quality, fresh protein in house. This is even more so with a Cryo-EM campaign and especially the case when the target is a membrane protein. In that latter respect we are indeed fortunate to have a dedicated and well-established membrane protein team led by Steven Harborne.
Figure 1: Typical Cryo-EM process that we run at Peak Proteins. We make data driven decisions through the various stages of the process in order to reduce risk and increase the chance of success.
The foundation of the service is a fantastic team of scientists and their wealth of protein science and structural biology expertise. Valerie Pye leads the Cryo-EM team in the Peak Proteins laboratories in the UK and Vikash Jha runs the equivalent team in the IniXium laboratories in Montreal, Canada. Both groups work seamlessly together now that the two companies comprise the Protein Science and Structural Biology division of Sygnature Discovery.
If our services are of interest and you have a project that would benefit from Cryo-EM, especially if it is proving to be a particularly challenging target, then please get in touch and one of our team would be happy to discuss your requirements. info@peakproteins.com
