Our Blog

Peak Proteins Blog Archives

Rapid Assessment of Membrane Protein Quality by Fluorescent Size Exclusion Chromatography

2025-08-05T13:58:56+00:00January 24th, 2023|Company News, Membrane Proteins, Our Blog, Peak Favourites, Protein Purification|

Researchers from Peak Proteins (part of Sygnature Discovery Ltd.) have recently published a research paper in the Journal of Visualized Experiments. The paper entitled “Rapid Assessment of Membrane Protein Quality by Fluorescent Size Exclusion Chromatography” was authored by Dr [...]

The Ligand That Can’t Decide…

2022-12-12T11:53:12+00:00July 28th, 2022|Our Blog|

Development of Selective Phosphatidylinositol 5‐Phosphate 4‐Kinase γ Inhibitors with a Non-ATP-competitive, Allosteric Binding Mode Helen K. Boffey, Timothy P. C. Rooney, Henriette M. G. Willems, Simon Edwards, Christopher Green, Tina Howard, Derek Ogg, Tamara Romero, Duncan E. Scott, David [...]

Wrestling with SUMO

2022-12-12T11:58:12+00:00June 29th, 2022|Our Blog|

Have you ever thought of using a solubility tag to enhance expression of your protein, considered using SUMO and then wondered,  which sequence should I use? and which version is most suitable for the expression host I’m using? It’s [...]

Alphafold: (Nearly) One Year On

2023-05-25T13:28:22+00:00April 28th, 2022|Our Blog, Protein Purification|

During 2020’s CASP14 challenge (Critical Assessment of Structure Prediction), Google’s DeepMind showcased Alphafold2, their revised protein folding model, and to say it was impressive is an understatement. The model successfully won the competition with a median Global Distance Test [...]

Go to Top