Category Archives for Cell Science
The intriguing world of the Intrinsically disordered proteins and why they are important as targets for drug discovery By Ariadna Juarez-Martinez PhD When we think about proteins, we usually picture them as having a well-defined, three-dimensional, globular shape; however, [...]
Introducing our newest piece of equipment; the Labfors5 benchtop bioreactor from Infors! By Ailsa Townley, Cell Scientist Over the past year we have been receiving increasing numbers of requests for larger final quantities of protein. Therefore, we have had [...]
What is Biotin? Biotin (or vitamin B7) is an essential coenzyme that is required by all organisms for life. Indeed, biotin’s name literally means ‘life giving’. Biotin is covalently linked near the active sites of four major classes of [...]
The closing date for this job vacancy has passed. Please visit our Join Us page for current vacancies. If you feel you have the skills and experience and would like to become part of our team please send your speculative CV to jobs@peakproteins.com. [...]
We are looking for a cell scientist to be part of our rapidly growing team involved in the generation of recombinant proteins for use in the pharmaceutical industry. Peak Proteins is a vibrant contract research organisation (CRO) that provides [...]
Following our collaboration last year with the Medicines Discovery Catapult and Retrogenix to advance understanding of the cellular mechanisms of infection by COVID-19, we have a recently published paper. We fulfilled the aims of the project to demonstrate a methodology [...]
A recombinant protein can be defined as “a modified or manipulated protein encoded by recombinant DNA”. A plasmid containing the gene of interest, in an appropriate expression vector, is expressed in a specific host expression system with the aim [...]
At Peak Proteins, we use mammalian, insect and bacterial cells grown in specialised culture media for the expression of recombinant proteins. A key focus for us is to ensure the expression systems we use are running optimally, in order [...]
Dr Mark Elvin discusses his recent publication: Metabolic profiling of Chinese hamster ovary cell cultures at different working volumes and agitation speeds using spin tube reactors, Biotechnology Progress, September/October 2020, Volume 36 No 5, Mauro Torres, Mark Elvin, Zeynep [...]
Our earlier BLOG outlined the benefits of using mammalian cells as an expression host, and here at Peak Proteins we routinely use the transient mammalian HEK293-6E suspension cell system licensed from the National Research Council of Canada. The use of [...]
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