Michela Pulix PhD

Senior Cell Scientist

Michela Pulix has significant experience from working in both academia and the biotech industry.

Michela Pulix PhD

More about Michela

Michela obtained a degree in Toxicology from the University of Cagliari, in the sunny island of Sardinia (Italy). After completing a master’s degree in Neuropychobiology, she won a studentship to do a work experience abroad, and so she decided to say goodbye to the sun and move to the UK. After spending 6 rainy months at the University of Liverpool, she decided she loved it there and remained to start her Wellcome Trust-funded PhD in Cellular and Molecular Physiology, working on a gene involved in brain development and microcephaly. After this, she moved to work in the gene therapy field, designing and engineering Adeno-associated virus (AAV) vectors and by optimising production in mammalian cells.

After 4 years in the gene therapy field (in both academia and industry), she spent 2 years working on DNA production and E.coli fermentations in an industrial setting. She finally joined Peak Proteins where she is now developing her expertise in recombinant protein production by gaining experience in the Cell Science team.

In her spare time, Michela likes exciting hobbies and activities such as crochet, gardening, books and puzzles. She is also constantly bullied by her cats who she claims she loves very much and wouldn’t change for the world.

Microcephaly with a disproportionate hippocampal reduction, stem cell loss and neuronal lipid droplet symptoms in Trappc9 KO mice
Neurobiol Dis. 2024 Mar:192:106431.
Aljuraysi S, Platt M, Pulix M, Poptani H, Plagge A.
DOI: 10.1016/j.nbd.2024.106431

Variable allelic expression of imprinted genes at the Peg13, Trappc9, Ago2 cluster in single neural cells.
Front Cell Dev Biol. 2022 Oct 12;10:1022422.
Claxton M, Pulix M, Seah MKY, Bernardo R, Zhou P, Aljuraysi S, Liloglou T, Arnaud P, Kelsey G, Messerschmidt DM, Plagge A.
DOI: 10.3389/fcell.2022.1022422

Molecular characterization of HEK293 cells as emerging versatile cell factories
Curr Opin Biotechnol. 2021
Pulix M, Lukashchuk V, Smith DC, Dickson AJ.
DOI: 10.1016/j.copbio.2021.05.001

Imprinted genes and hypothalamic functions.
Masterclass in Neuroendocrinology (Springer), pp. 265-294 (2020).
Pulix, M., Plagge, A.

Reductions in hypothalamic Gfap expression, glial cells and α-tanycytes in lean and hypermetabolic Gnasxl- deficient mice.
Molecular Brain, 14;9:39 (2016).
Holmes, A. P., Wong, S. Q., Pulix, M., Johnson, K., Horton, N. S., Thomas, P., de Magalhães J. P., Plagge, A.
DOI: 10.1186/s13041-016-0219-1